Laboratory of Tissue Regeneration and Inflammation

Featured Publications

Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation.

Subudhi I, Konieczny P, Prystupa A, et al.,

Immunity, 2024

DOI PMID

Interleukin-17 governs hypoxic adaptation of injured epithelium.

Konieczny P, Xing Y, et al.,

Science, 2022

DOI PMID

Immune-Epithelial Cross Talk in Regeneration and Repair.

Guenin-Mace L, Konieczny P and Naik S

Annual Review of Immunology, 2023

DOI PMID

All Publications

Peripheral immune-inducer dendritic cells drive early-life allergic inflammation

Yue Xing, Ilana Reznikov, Abonti Nur Ahmed, Ikjot Sidhu, Jill Wisnewski, Asma Farhat, Aleksandr Prystupa, Piotr Konieczny, Kody Mansfield, Melissa L. Cooper, Stephen T. Yeung, Madeline Kim, Sophia Adeghe, Katherine D. Gaines, Meredith Manson, Ji Hyun Sim, Qingrong Huang, Ata S. Moshiri, Kamal M. Khanna, Theresa T. Lu, Emma Guttman-Yassky, Amanda W. Lund, Niroshana Anandasabapathy & Shruti Naik

Nature, 2026

DOI

PD-1 is requisite for skin TRM cell formation and specification by TGFβ

K. Sanjana P. Devi, Eric Wang, Abhinav Jaiswal, Piotr Konieczny, Tae-Gyun Kim, Christopher J. Nirschl, Akanksha Verma, Yong Liu, Julia Milczanowski, Susan N. Christo, Luke C. Gandolfo, Karyn Haitz, Trupti D. Vardam, Pinru Wu, Sandra L. King, Sze-Wah Tse, Komal Pradhan, Xiaodong Jiang, Tian Tian, Robert C. Fuhlbrigge, Chrysalyne D. Schmults, Rachael A. Clark, Thomas S. Kupper, Gordon J. Freeman, Laura K. Mackay, Shruti Naik, Evan W. Newell, Olivier Elemento, Mayte Suarez-Farinas & Niroshana Anandasabapathy

Nature Immunology, 2025

DOI PMID

Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation.

Subudhi I, Konieczny P, Prystupa A, et al.,

Immunity, 2024

DOI PMID

Cis-regulatory arbitrators of regeneration.

Konieczny P, Naik S.

Cell Stem Cell, 2023

DOI PMID

Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems.

Castillo RL, Sidhu I, Dolgalev I, Chu T, Prystupa A, Subudhi I, Yan D, Konieczny P, Hsieh B, Haberman RH, Selvaraj S, Shiomi T, Medina R, Girija PV, Heguy A, Loomis CA, Chiriboga L, Ritchlin C, Garcia-Hernandez ML, Carucci J, Meehan SA, Neimann AL, Gudjonsson JE, Scher JU, Naik S.

Science Immunology, 2023

DOI PMID

Immune-Epithelial Cross Talk in Regeneration and Repair.

Guenin-Mace L, Konieczny P and Naik S

Annual Review of Immunology, 2023

DOI PMID

Interleukin-17 governs hypoxic adaptation of injured epithelium.

Konieczny P, Xing Y, et al.,

Science, 2022

DOI PMID

Loss of epidermal MCPIP1 is associated with aggressive squamous cell carcinoma.

Szukala W, Lichawska-Cieslar A, Pietrzycka R, Kulecka M, Rumienczyk I, Mikula M, Chlebicka I, Konieczny P, Dziedzic K, Szepietowski JC, Fontemaggi G, Rys J, Jura J.

Journal of Experimental & Clinical Cancer Research, 2021

DOI PMID

Healing without scarring.

Konieczny P, Naik S.

Science, 2021

DOI PMID

Warp Speed Ahead! Technology-Driven Breakthroughs in Skin Immunity and Inflammatory Disease.

Konieczny P, Naik S.

Journal of Investigative Dermatology, 2021

DOI PMID